Adenosine Deaminase (ADA)

Test/Profile Name

Adenosine Deaminase (ADA)

Test/Profile Code

T001447

Clinical Usefullness

To help detect or rule out a Mycobacterium tuberculosis infection in pleural fluid in order to assist in the diagnosis of tuberculosis and rarely to detect the infection in other body fluids such as peritoneal fluid or cerebrospinal fluid (CSF).


Synonyms (Also knowns as)

ADA

Adenosine Deaminase


Specimen Type and Minimal Volume

Pleural Fluid , Serum, CSF : 0.3mL

Forms

Not required

Test Equipment

Biosystem BTS - 330

Test Method

Adenosine Glutamate dehydrogenase

Reference Range

Peural Fluid : 0 – 33 U/L

Include Test

N/A

Reporting Time (Turn Around Time; TAT)

8 hrs

Clinical Information

Adenosine deaminase (ADA) is a protein that is produced by cells throughout the body and is associated with the activation of lymphocytes. Conditions that trigger the immune system, such as an infection by Mycobacterium tuberculosis, may cause increased amounts of ADA to be produced in the areas where the bacteria are present. This test measures the amount of adenosine deaminase present in pleural fluid in order to help diagnose a tuberculosis infection of the pleurae.


Related Disease/Condition

Tuberculosis
Cancer (particularly lymphomas)
Pulmonary embolus
Sarcoidosis

Related Test

Fluid for AFB